Find everything you need to know about ondansetron (Zofran), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about ondansetron (Zofran) at

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Specific studies have shown that there are no interactions when ondansetron is administered with alcohol, temazepam, furosemide, alfentanil, tramadol, morphine, lidocaine, thiopental or propofol. Ondansetron is metabolised by multiple hepatic cytochrome P-450 enzymes: CYP3A4, CYP2D6 and … Ondansetron own mechanism of action as a serotonin inhibitor seems to be the one responsible for these behavioral changes in alcohol consumption. Alcohol craving is in fact believed to be caused by an imbalance between the two neurotransmitters dopamine and serotonin. Ondansetron helps to prevent nausea and vomiting due to chemotherapy, radiation, and surgery. This eMedTV page takes a look at how ondansetron works to block serotonin, and also lists possible side effects and general dosing guidelines for the drug. 2013-02-21 ACT-Ondansetron: Ondansetron belongs to the class of medications called 5-HT3 receptor antagonists.

Common interactions include death among females and chronic kidney disease among males. The phase IV clinical study is created by eHealthMe based on reports of 5,436 people who take Amlodipine and Ondansetron from the FDA, and is updated regularly. 2020-08-11 2015-08-08 Ondansetron is a potent and highly specific antagonist of the 5-HT3 serotonin receptor. The objective of the current trial was to determine if the addition of ondansetron to the combination of metoclopramide, dexamethasone, and lorazepam (MDL) could improve the control … 2014-04-16 2018-09-12 This major side effect is often managed with a competitive serotonin antagonist, ondansetron—contributing a pharmacodynamic interaction. Potential also exists for a pharmacokinetic interaction. Ondansetron is, in part, metabolised by the CYP2D6 iso-enzyme system—an iso-enzyme system responsible for formation of an active tramadol metabolite that has analgesic effect by binding … Ondansetron is an anti-sickness medicine (sometimes called an antiemetic) that is mainly used in hospitals to help with nausea and vomiting associated with cancer treatments or operations under Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for ONDANSETRON. Drug interactions are reported among people who take Wellbutrin xl and Ondansetron.

Taking ondansetron along with other medications, such as carbamazepine or phenytoin, can decrease the level of ondansetron in your blood. However, for most people, this interaction does not cause any problems.

Use of ondansetron has been associated with prolongation of the QT interval, which can lead to a potentially fatal heart rhythm known as torsades de pointes. Although this may happen in any person with any formulation, the risk is most salient with the injectable (intravenous) form of the drug and increases with dose.

Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for Taking ondansetron along with other medications, such as carbamazepine or phenytoin, can decrease the level of ondansetron in your blood. However, for most people, this interaction does not cause any problems.

the anti-nausea drug Zofran (ondansetron, ondansetron hydrochloride and their generics). Severe Interactions. Tekniken är etablerad sedan många år tillbaka

The phase IV clinical study is created by eHealthMe based on reports of 5,436 people who take Amlodipine and Ondansetron from the FDA, and is updated regularly. 2020-08-11 2015-08-08 Ondansetron is a potent and highly specific antagonist of the 5-HT3 serotonin receptor. The objective of the current trial was to determine if the addition of ondansetron to the combination of metoclopramide, dexamethasone, and lorazepam (MDL) could improve the control … 2014-04-16 2018-09-12 This major side effect is often managed with a competitive serotonin antagonist, ondansetron—contributing a pharmacodynamic interaction. Potential also exists for a pharmacokinetic interaction. Ondansetron is, in part, metabolised by the CYP2D6 iso-enzyme system—an iso-enzyme system responsible for formation of an active tramadol metabolite that has analgesic effect by binding … Ondansetron is an anti-sickness medicine (sometimes called an antiemetic) that is mainly used in hospitals to help with nausea and vomiting associated with cancer treatments or operations under Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for ONDANSETRON. Drug interactions are reported among people who take Wellbutrin xl and Ondansetron. Common interactions include eating disorder among females and plasma cell myeloma among males.

This drug gene interaction (DGI) pertains to the interaction between the CYP2D6 gene and ondansetron (Zofran®). Ondansetron belongs to a class of drugs known as serotonin receptor 5-HT 3 antagonists and are used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. Although this interaction has not been studied, predictions about the interaction can be made based on the metabolic pathway of ondansetron. Ondansetron is a substrate of the drug efflux transporter P-glycoprotein (PGP) and of the hepatic isoenzyme CYP3A4; boceprevir is an inhibitor of both the efflux protein and the isoenzyme.
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2-Rarely and predominantly with intravenous ondansetron, transient ECG changes including QT interval prolongation have been reported.

Severe Interactions. Tekniken är etablerad sedan många år tillbaka Interactions between glioma and pregnancy: insight from a 52-case multicenter series.
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Medscape - Nausea & vomiting dosing for Zofran, Zuplenz (ondansetron), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Ondansetron had minimal effects on subjects receiving placebo alcohol. These data suggest that the reductions in alcohol consumption observed in animals and humans treated with ondansetron may be mediated by increases in subjective intoxication, and/or increases in the aversive effects of alcohol.

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2014-04-16

In the Response to Comment section, we hav View drug interactions between Ambien and ondansetron. These medicines may also interact with certain foods or diseases. This report displays the potential drug interactions for the following 2 drugs: Edit list (add/remove drugs) No interac WebMD provides information about interactions between Azithromycin Oral and qt-prolonging-agents-ondansetron. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or Find patient medical information for ondansetron oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Consult your pharmacist or physician.